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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Bis-NH2-C1-PEG3, also known as PROTAC Linker 24, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Appearance: colorless to light yellow liquid
Molecular formula: C10H24N2O3
Molecular weight: 220.31
Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
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BM-PEG3 is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling targeted degradation.
PEG-based PROTAC linker
For research use only
Purity: 98.0%
Molecular weight: 352.34
Molecular formula: C16H20N2O7
Appearance: White to light yellow solid
Storage as powder: -20°C for 3 years, 4°C for 2 years
Storage in solvent: -80°C for 6 months, -20°C for 1 month
Solubility in DMSO: 100 mg/mL (in vitro)
Solubility in 10% DMSO, 90% corn oil: ≥ 2.5 mg/mL (in vivo)
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Azido-PEG3-C6-Cl is a PEG-based linker bearing an azide group used for click chemistry and PROTAC synthesis. It facilitates conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), providing a versatile building block for bioconjugation and linker design.
Contains an azide functional group for efficient CuAAC reactions.
Compatible with strain-promoted azide-alkyne cycloaddition for catalyst-free conjugation.
PEG3 spacer improves solubility and provides linker flexibility.
Terminal chlorohexyl enables further chemical modification.
High purity and characterized molecular data support synthetic use.
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Triphenyltin chloride-d15 is the deuterium-labeled analogue of triphenyltin chloride used as a stable isotope reference standard and research reagent for analytical chemistry, mass spectrometry, and isotopic labeling studies. It is supplied as a powder and characterized by high isotopic enrichment and chemical purity.
Deuterium-labeled standard for analytical and mass spectrometry applications.
High chemical purity and isotopic enrichment for accurate quantitation.
Supplied as a stable powder with defined storage conditions.
Useful as an internal standard and reference material in method development.
Characterized by molecular formula C18D15ClSn and molecular weight 400.57 g/mol.
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